Summary

Name DGKD
Full Name Diacylglycerol kinase delta
Synonyms DAG kinase delta, 130 kDa diacylglycerol kinase, Diglyceride kinase delta, DGK-delta | KIAA0145
Primary ID Q16760
Links - -
Type protein
Relations 2
Function Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:12200442, PubMed:23949095). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). By controlling the levels of diacylglycerol, regulates for instance the PKC and EGF receptor signaling pathways and plays a crucial role during development (By similarity). May also regulate clathrin-dependent endocytosis (PubMed:17880279).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation DGKD 0.373
Publications: 2 Organism: Chlorocebus Aethiops