Summary

Name IMMT
Full Name MICOS complex subunit MIC60
Synonyms Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89 | HMP, MIC60, MINOS2
Primary ID Q16891
Links - -
Type protein
Relations 2
Function Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180).

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation IMMT 0.2
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png binding PINK1 0.411
Publications: 1 Organism: In Vitro