Summary

Name DOK7
Full Name Protein Dok-7
Synonyms Downstream of tyrosine kinase 7 | C4orf25
Primary ID Q18PE1
Links - -
Type protein
Relations 6
Function Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation DOK7 0.746
Publications: 3 Organism: Mus Musculus
+ up-regulates img/direct-activation.png binding MUSK 0.746
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding CRK 0.365
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding CRKL 0.351
Publications: 1 Organism: Mus Musculus