Summary

Name BRDT
Full Name Bromodomain testis-specific protein
Synonyms Cancer/testis antigen 9, CT9, RING3-like protein |
Primary ID Q58F21
Links - -
Type protein
Relations 3
Inhibitors JQ1
Function Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis (PubMed:22464331, PubMed:22901802). Required in late pachytene spermatocytes

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png relocalization BRDT 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png chemical inhibition BRDT 0.8
Publications: 1 Organism: In Vitro
+ up-regulates quantity img/direct-activation.png binding EIF4EBP1 0.2
Publications: 1 Organism: Homo Sapiens