3.0
Summary
| Name |  LRIF1
|
| Full Name | Ligand-dependent nuclear receptor-interacting factor 1 |
| Synonyms | HP1-binding protein enriched in inactive X chromosome protein 1, HBiX1, Receptor-interacting factor 1 | C1orf103, RIF1 |
| Primary ID | Q5T3J3 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin (PubMed:23542155). Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases (PubMed:17455211). Also required for silencing of the DUX4 locus in somatic cells (PubMed:32467133). {ECO:0000269|PubMed:17455211, ECO:0000269|PubMed:23542155, ECO:0000269|PubMed:32467133}. |
ubiquitination