+ |
PINK1 | down-regulates quantity by destabilization
phosphorylation
|
ZNF746 |
0.384 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273724 |
Ser322 |
QATRFFPsPAQEGAW |
Homo sapiens |
SH-SY5Y Cell |
pmid |
sentence |
28122242 |
PINK1 is required for Parkin ubiquitination and degradation of PARIS. PINK1 interacts with and phosphorylates serines 322 and 613 of PARIS to control its ubiquitination and clearance by parkin. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273725 |
Ser613 |
APPDPFKsPASKGPL |
Homo sapiens |
SH-SY5Y Cell |
pmid |
sentence |
28122242 |
PINK1 is required for Parkin ubiquitination and degradation of PARIS. PINK1 interacts with and phosphorylates serines 322 and 613 of PARIS to control its ubiquitination and clearance by parkin. |
|
Publications: |
2 |
Organism: |
Homo Sapiens |
+ |
PRKN | down-regulates quantity by destabilization
ubiquitination, polyubiquitination
|
ZNF746 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-273726 |
|
|
Homo sapiens |
SH-SY5Y Cell |
pmid |
sentence |
28122242 |
PINK1 is required for Parkin ubiquitination and degradation of PARIS. PINK1 interacts with and phosphorylates serines 322 and 613 of PARIS to control its ubiquitination and clearance by parkin. |
|
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-272758 |
|
|
Homo sapiens |
SH-SY5Y Cell |
pmid |
sentence |
21376232 |
. Parkin ubiquitinates and regulates the ubiquitin proteasomal degradation of PARIS |
|
Publications: |
2 |
Organism: |
Homo Sapiens |