| + |
ERAP2 | down-regulates quantity
chemical modification
|
oligopeptide |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272495 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15908954 |
The generation of many HLA class I peptides entails a final trimming step in the endoplasmic reticulum that, in humans, is accomplished by two 'candidate' aminopeptidases | We show here that one of these, ERAP1, was unable to remove several N-terminal amino acids that were trimmed efficiently by the second enzyme, ERAP2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
ERAP2 | up-regulates quantity
chemical modification
|
peptide antigen |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272496 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 15908954 |
The generation of many HLA class I peptides entails a final trimming step in the endoplasmic reticulum that, in humans, is accomplished by two 'candidate' aminopeptidases | We show here that one of these, ERAP1, was unable to remove several N-terminal amino acids that were trimmed efficiently by the second enzyme, ERAP2. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |