Relation Results

Summary

Name INO80C
Full Name INO80 complex subunit C
Synonyms IES6 homolog, hIes6 | C18orf37
Primary ID Q6PI98
Links - -
Type protein
Relations 1
Function Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA re ...
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Type: Score: Layout: SPV 
0.651INO80CINO80 complex

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Relations
Regulator
Mechanism
target
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+ INO80Cform complex img/form-complex.png binding INO80 complex 0.651
Identifier Residue Sequence Organism Cell Line
SIGNOR-270851 Homo sapiens
pmid sentence
Here, we have systematically investigated the involvement of the catalytic subunit of the human INO80 complex during unchallenged replication and under replication stress by following the effects of its depletion on cell survival, S-phase checkpoint activation, the fate of individual replication forks, and the consequences of fork collapse. We report that INO80 was specifically needed for efficient replication elongation, while it was not required for initiation of replication.
Publications: 1 Organism: Homo Sapiens
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