Summary

Name DNMBP
Full Name Dynamin-binding protein
Synonyms Scaffold protein Tuba | ARHGEF36, KIAA1010, TUBA
Primary ID Q6XZF7
Links - -
Type protein
Relations 1
Function Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells (PubMed:19767742, PubMed:17015620). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (PubMed:20479467). Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity).

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Relations

Regulator Mechanism target score ℹ
+ DNMBPup-regulates activity img/direct-activation.png guanine nucleotide exchange factor CDC42 0.554
Publications: 1 Organism: Homo Sapiens