Summary

Name USP45
Full Name Ubiquitin carboxyl-terminal hydrolase 45
Synonyms Deubiquitinating enzyme 45, Ubiquitin thioesterase 45, Ubiquitin-specific-processing protease 45 |
Primary ID Q70EL2
Links - -
Type protein
Relations 2
Function Catalyzes the deubiquitination of SPDL1 (PubMed:30258100). Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites (PubMed:25538220). May be involved in the maintenance of photoreceptor function (PubMed:30573563). May play a role in normal retinal development (By similarity). Plays a role in cell migration (PubMed:30258100).

Viewer

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png deubiquitination ERCC4/ERCC1 0.541
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png deubiquitination SPDL1 0.2
Publications: 1 Organism: Homo Sapiens