Relation Results

Summary

Name SLC36A1
Full Name Proton-coupled amino acid transporter 1
Synonyms Proton/amino acid transporter 1, hPAT1, Solute carrier family 36 member 1 | PAT1
Primary ID Q7Z2H8
Links - -
Type protein
Relations 3
Function Neutral amino acid/proton symporter. Has a pH-dependent electrogenic transport activity for small amino acids such as glycine, alanine and proline. Be ...
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Type: Score: Layout: SPV 
0.80.80.8SLC36A1glycinealanineproline

Relations

Regulator
Mechanism
target
score
+ up-regulates quantity img/direct-activation.png relocalization glycine 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-264737 Homo sapiens
pmid sentence
Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.|The first member of the SLC36 family, present in both intracellular and plasma membranes, was identified independently as a lysosomal amino acid transporter (LYAAT1) responsible for the export of lysosomal proteolysis products into the cytosol and as a proton/amino acid transporter (PAT1) responsible for the absorption of amino acids in the gut.
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png relocalization alanine 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-264739 Homo sapiens
pmid sentence
Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.|The first member of the SLC36 family, present in both intracellular and plasma membranes, was identified independently as a lysosomal amino acid transporter (LYAAT1) responsible for the export of lysosomal proteolysis products into the cytosol and as a proton/amino acid transporter (PAT1) responsible for the absorption of amino acids in the gut.
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png relocalization proline 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-264741 Homo sapiens
pmid sentence
Both PAT1 and PAT2 mediate 1:1 symport of protons and small neutral amino acids such as glycine, alanine, and proline.|The first member of the SLC36 family, present in both intracellular and plasma membranes, was identified independently as a lysosomal amino acid transporter (LYAAT1) responsible for the export of lysosomal proteolysis products into the cytosol and as a proton/amino acid transporter (PAT1) responsible for the absorption of amino acids in the gut.
Publications: 1 Organism: Homo Sapiens
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