| Name
|
 DTX2
|
| Full Name |
Probable E3 ubiquitin-protein ligase DTX2 |
| Synonyms |
Protein deltex-2, Deltex2, hDTX2, RING finger protein 58, RING-type E3 ubiquitin transferase DTX2 | KIAA1528, RNF58 |
| Primary ID |
Q86UW9 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
1 |
| Function |
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |
4.0
ubiquitination