Summary

Name WDR75
Full Name WD repeat-containing protein 75
Synonyms U3 small nucleolar RNA-associated protein 17 homolog | UTP17
Primary ID Q8IWA0
Links - -
Type protein
Relations 1
Function Ribosome biogenesis factor. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding UTP-A complex 0.839
Publications: 1 Organism: Homo Sapiens