Summary

Name MSL3
Full Name Male-specific lethal 3 homolog
Synonyms Male-specific lethal-3 homolog 1, Male-specific lethal-3 protein-like 1, MSL3-like 1 | MSL3L1
Primary ID Q8N5Y2
Links - -
Type protein
Relations 1
Function Has a role in chromatin remodeling and transcriptional regulation (PubMed:20018852, PubMed:20657587, PubMed:20943666, PubMed:21217699, PubMed:30224647). Has a role in X inactivation (PubMed:21217699). Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure (PubMed:16227571, PubMed:20657587, PubMed:16543150, PubMed:30224647). Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex (PubMed:20657587, PubMed:20943666).

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Relations

Regulator Mechanism target score ℹ
+ MSL3form complex img/form-complex.png binding MSL acetyltransferase 0.813
Publications: 1 Organism: Homo Sapiens
Tissue: HeLa Cell