Summary

Name GLIS1
Full Name Zinc finger protein GLIS1
Synonyms GLI-similar 1 |
Primary ID Q8NBF1
Links - -
Type protein
Relations 2
Function Acts as both a repressor and activator of transcription (PubMed:21654807). Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity). By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807). Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation GLIS1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png transcriptional regulation WNT5A 0.25
Publications: 1 Organism: Homo Sapiens