| + |
FBXO15 | down-regulates quantity by destabilization 
binding
|
CRLS1 |
0.336 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272170 |
|
|
Homo sapiens |
A549-CR Cell |
| pmid |
sentence |
| 24703837 |
Fbxo15 Targets CLS1 Protein for Ubiquitination and Degradation to Disrupt Mitochondrial Function. S. aureus infection induces expression of a kinase, PINK1, that phosphorylates an indispensable protein CLS1, which in turn triggers CLS1 ubiquitination and degradation by the F box protein (SCFFbxo15). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
Cullin 1-RBX1-Skp1 | down-regulates quantity by destabilization
polyubiquitination
|
FBXO15 |
0.501 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272172 |
|
|
Homo sapiens |
A549-CR Cell |
| pmid |
sentence |
| 24703837 |
Fbxo15 Targets CLS1 Protein for Ubiquitination and Degradation to Disrupt Mitochondrial Function. S. aureus infection induces expression of a kinase, PINK1, that phosphorylates an indispensable protein CLS1, which in turn triggers CLS1 ubiquitination and degradation by the F box protein (SCFFbxo15). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
FBXO15 | up-regulates activity 
binding
|
Cullin 1-RBX1-Skp1 |
0.501 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-272171 |
|
|
Homo sapiens |
A549-CR Cell |
| pmid |
sentence |
| 24703837 |
Fbxo15 Targets CLS1 Protein for Ubiquitination and Degradation to Disrupt Mitochondrial Function. S. aureus infection induces expression of a kinase, PINK1, that phosphorylates an indispensable protein CLS1, which in turn triggers CLS1 ubiquitination and degradation by the F box protein (SCFFbxo15). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
FBXO15
- 
- 