Summary

Name CSNK2A3
Full Name Casein kinase II subunit alpha 3
Synonyms CK II alpha 3, Casein kinase II alpha 1 polypeptide pseudogene | CSNK2A1P
Primary ID Q8NEV1
Links - -
Type protein
Relations 6
Function Probable catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Amplification-dependent oncogene; promotes cell proliferation and tumorigenesis by down-regulating expression of the tumor suppressor protein, PML. May play a role in the pathogenesis of the lung cancer development and progression.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation SCN2A 0.2
Publications: 3 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation F8 0.2
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png phosphorylation FGF14 0.272
Publications: 2 Organism: Homo Sapiens