3.0
Summary
| Name |  GRPEL2
|
| Full Name | GrpE protein homolog 2, mitochondrial |
| Synonyms | Mt-GrpE#2 | |
| Primary ID | Q8TAA5 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | GRPEL2 | form complex 
binding
|
TIM23 complex | 0.499 |
| Publications: | 1 | |||