Summary

Name NRG4
Full Name Pro-neuregulin-4, membrane-bound isoform
Synonyms Pro-NRG4
Primary ID Q8WWG1
Links - -
Type protein
Relations 2
Function Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding ERBB4 0.684
Publications: 2 Organism: Homo Sapiens
Tissue: Muscle