Summary

Name UTP4
Full Name U3 small nucleolar RNA-associated protein 4 homolog
Synonyms Cirhin, UTP4 small subunit processome component | CIRH1A, cPERP-E, KIAA1988
Primary ID Q969X6
Links - -
Type protein
Relations 1
Function Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted d Involved in SSU pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre-ribosomal RNA transcription by RNA polymerase (PubMed:17699751, PubMed:19732766, PubMed:34516797). May be a transcriptional regulator (PubMed:22916032).

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding UTP-A complex 0.2
Publications: 1 Organism: Homo Sapiens