Relation Results

Summary

Name CNOT6L
Full Name CCR4-NOT transcription complex subunit 6-like
Synonyms Carbon catabolite repressor protein 4 homolog B | CCR4B
Primary ID Q96LI5
Links - -
Type protein
Relations 1
Function Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major ...
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Type: Score: Layout: SPV 
0.808CNOT6LCCR4-NOT complex

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+ CNOT6Lform complex img/form-complex.png binding CCR4-NOT complex 0.808
Identifier Residue Sequence Organism Cell Line
SIGNOR-268311 Homo sapiens
pmid sentence
In the present study, we examine the composition of the human Ccr4-Not complex in an in-depth proteomic approach using stable cell lines expressing tagged CNOT proteins. We find at least four different variants of the human complex, consisting of seven stable core proteins and mutually exclusive associated mRNA deadenylase subunits. Interestingly, human CNOT4 is in a separate approximately 200 kDa complex. Furthermore, analyses of associated proteins indicate involvement of Ccr4-Not complexes in splicing, transport and localization of RNA molecules.
Publications: 1 Organism: Homo Sapiens
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