3.0
Summary
| Name |  MUS81View Modifications |
| Full Name | Crossover junction endonuclease MUS81 |
| Synonyms | EC 3.1.22.- | |
| Primary ID | Q96NY9 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. Plays an essential role in mitosis for the processing of stalled or collapsed replication forks (PubMed:28575661). {ECO:0000269|PubMed:11741546, ECO:0000269|PubMed:12374758, ECO:0000269|PubMed:12686547, ECO:0000269|PubMed:12721304, ECO:0000269|PubMed:14617801, ECO:0000269|PubMed:15805243, ECO:0000269|PubMed:17289582, ECO:0000269|PubMed:19595721, ECO:0000269|PubMed:19596235, ECO:0000269|PubMed:28575661}. |
phosphorylation