| + |
SEC62 | up-regulates 
|
Protein_translocation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265281 |
|
|
|
|
| pmid |
sentence |
| 22375059 |
We demonstrated, with a similar knockdown approach, a precursor-specific involvement of mammalian Sec63 in the initial phase of co-translational protein transport into the ER. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265280 |
|
|
|
|
| pmid |
sentence |
| 22375059 |
Silencing the SEC62 gene inhibits post-translational transport of small presecretory proteins into the human ER |
|
| Publications: |
2 |
| + |
SEC63 | up-regulates activity 
binding
|
SEC62 |
0.959 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265273 |
|
|
Homo sapiens |
Hep-G2 Cell |
| pmid |
sentence |
| 23287549 |
Sec63 was identified as a novel substrate and binding partner of protein kinase CK2. We identified serine 574, serine 576 and serine 748 as CK2 phosphorylation sites. Phosphorylation of Sec63 by CK2 enhanced its binding to Sec62. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SEC61 complex | up-regulates activity
binding
|
SEC62 |
0.739 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265275 |
|
|
|
|
| pmid |
sentence |
| 33925740 |
This is where allosteric effectors of the Sec61 complex (BiP together with Sec62/Sec63 complex or TRAP complex) (Figure 2 and Figure 5) and auxiliary membrane protein insertases (EMC and TMCO1 complex) join the game |
|
| Publications: |
1 |
3.0
SEC62
- 
- 