Summary

Name SERPINI1
Full Name Neuroserpin
Synonyms Peptidase inhibitor 12, PI-12, Serpin I1 | PI12
Primary ID Q99574
Links - -
Type protein
Relations 2
Function Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin (PubMed:9442076, PubMed:26329378, PubMed:19265707, PubMed:19285087, PubMed:11880376). May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable).

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Relations

Regulator Mechanism target score
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination SERPINI1 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination SERPINI1 0.304
Publications: 1 Organism: Homo Sapiens