Name	PKMYT1 View Modifications
Full Name	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Synonyms	Myt1 kinase \| MYT1
Primary ID	Q99640
Links	- -
Type	protein
Relations	7
Function	Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.