4.0
Summary
| Name |  KIAA0586
|
| Full Name | Protein TALPID3 |
| Synonyms | TALD3_HUMAN | TALPID3 |
| Primary ID | Q9BVV6 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (PubMed:24421332). Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (By similarity). |
ubiquitination