+ |
AKT | down-regulates
phosphorylation
|
CDCA7 |
0.2 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-199776 |
Thr163 |
SRRPRRRtFPGVASR |
Homo sapiens |
|
pmid |
sentence |
23166294 |
The prosurvival kinase akt phosphorylates cdca7 at threonine 163, promoting binding to 14-3-3, dissociation from myc, and sequestration to the cytoplasm. we have mapped the domains of interaction and have discovered that akt phosphorylates cdca7 near this contact region, leading to loss of its association with myc, binding to 14-3-3 proteins, and exclusion from the nucleus. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
AKT1 | down-regulates
phosphorylation
|
CDCA7 |
0.345 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-252533 |
Thr163 |
SRRPRRRtFPGVASR |
Homo sapiens |
|
pmid |
sentence |
23166294 |
The prosurvival kinase akt phosphorylates cdca7 at threonine 163, promoting binding to 14-3-3, dissociation from myc, and sequestration to the cytoplasm. we have mapped the domains of interaction and have discovered that akt phosphorylates cdca7 near this contact region, leading to loss of its association with myc, binding to 14-3-3 proteins, and exclusion from the nucleus. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |