Summary

Name UCK2
Full Name Uridine-cytidine kinase 2
Synonyms UCK 2, Cytidine monophosphokinase 2, Testis-specific protein TSA903, Uridine monophosphokinase 2 | UMPK
Primary ID Q9BZX2
Links - -
Type protein
Relations 9
Pathways Nucleotide Salvage
Function Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

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Relations

Regulator Mechanism target score ℹ
+ UCK2down-regulates quantity img/direct_inhibition.png chemical modification ATP(4-) 0.8
Publications: 1 Organism: Homo Sapiens
+ UCK2up-regulates quantity img/direct-activation.png chemical modification ADP(3-) 0.8
Publications: 1 Organism: Homo Sapiens
+ UCK2down-regulates quantity img/direct_inhibition.png chemical modification cytidine 0.8
Publications: 1 Organism: Homo Sapiens
+ UCK2up-regulates quantity img/direct-activation.png chemical modification cytidine 5'-monophosphate(2-) 0.8
Publications: 2 Organism: Homo Sapiens,
+ UCK2down-regulates quantity img/direct_inhibition.png chemical modification uridine 0.8
Publications: 1 Organism: Homo Sapiens
+ UCK2up-regulates quantity img/direct-activation.png chemical modification uridine 5'-monophosphate(2-) 0.8
Publications: 2 Organism: Homo Sapiens,
+ METTL3up-regulates quantity by stabilization img/direct-activation.png post transcriptional regulation UCK2 0.2
Publications: 1