Summary

Name WNT10A
Full Name Protein Wnt-10a
Synonyms WN10A_HUMAN
Primary ID Q9GZT5
Links - -
Type protein
Relations 5
Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development (PubMed:17847007, PubMed:28589954). Required for normal tooth development (PubMed:17847007, PubMed:29178643, PubMed:28589954). Required for normal postnatal development and maintenance of tongue papillae and sweat ducts (PubMed:28589954). Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium (PubMed:28589954). Required for normal hair follicle function (PubMed:28589954).

Viewer

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding LRP5 0.566
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png CTNNB1 0.479
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding LRP6 0.555
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding FZD3 0.608
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/indirect_inhibition.png WNT10A 0.338
Publications: 1 Organism: Mus Musculus