Summary

Name FGF23
Full Name Fibroblast growth factor 23
Synonyms FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor | HYPF
Primary ID Q9GZV9
Links - -
Type protein
Relations 1
Function Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

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Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation FGF23 0.626
Publications: 1 Organism: Homo Sapiens