4.0
Summary
| Name |  MKRN2
|
| Full Name | E3 ubiquitin-protein ligase makorin-2 |
| Synonyms | RING finger protein 62, RING-type E3 ubiquitin transferase makorin-2 | RNF62 |
| Primary ID | Q9H000 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (By similarity). Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses (By similarity). Plays a role in the regulation of spermiation and in male fertility (By similarity). |
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ubiquitination
ubiquitination