Summary

Name SYT4
Full Name Synaptotagmin-4
Synonyms Synaptotagmin IV, SytIV | KIAA1342
Primary ID Q9H2B2
Links - -
Type protein
Relations 1
Function Synaptotagmin family member which does not bind Ca(2+) (PubMed:23999003) (By similarity). Involved in neuronal dense core vesicles (DCVs) mobility through its interaction with KIF1A. Upon increased neuronal activity, phosphorylation by MAPK8/JNK1 destabilizes the interaction with KIF1A and captures DCVs to synapses (By similarity). Plays a role in dendrite formation by melanocytes (PubMed:23999003).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation SYT4 0.424
Publications: 1 Organism: Rattus Norvegicus