Summary

Name FAM83D
Full Name Protein FAM83D
Synonyms Spindle protein CHICA | C20orf129
Primary ID Q9H4H8
Links - -
Type protein
Relations 2
Function Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117). May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692). May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22 (PubMed:18485706). {ECO:0000269|PubMed:18485706, ECO:0000269|PubMed:24344117, ECO:0000269|PubMed:25646692}.

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Relations

Regulator Mechanism target score
+ up-regulates quantity img/direct-activation.png binding CSNK1A1 0.391
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png binding CSNK1A1L 0.2
Publications: 1 Organism: Homo Sapiens