Relation Results

Name	ESRP2
Full Name	Epithelial splicing regulatory protein 2
Synonyms	RNA-binding motif protein 35B, RNA-binding protein 35B \| RBM35B
Primary ID	Q9H6T0
Links	- -
Type	protein
Relations	1
Function	mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. {ECO:0000269\|PubMed:19285943}.