3.0
Summary
| Name |  NLRC4
|
| Full Name | NLR family CARD domain-containing protein 4 |
| Synonyms | CARD, LRR, and NACHT-containing protein, Clan protein, Caspase recruitment domain-containing protein 12, Ice protease-activating factor, Ipaf | CARD12, CLAN, CLAN1, IPAF |
| Primary ID | Q9NPP4 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed:15107016). The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria (By similarity). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
binding
transcriptional regulation