Summary

Name RIC8B
Full Name Chaperone Ric-8B
Synonyms Brain synembryn, hSyn, Synembryn-B |
Primary ID Q9NVN3
Links - -
Type protein
Relations 1
Function Chaperone that specifically binds and folds nascent G(s) G-alpha proteins (GNAS and GNAL) prior to G protein heterotrimer formation, promoting their association with the plasma membrane (By similarity). Also acts as a guanine nucleotide exchange factor (GEF) for G(s) proteins by stimulating exchange of bound GDP for free GTP (By similarity). Acts as an important component for odorant signal transduction by mediating GNAL (G(olf)-alpha) folding, thereby promoting-dependent cAMP accumulation in olfactory sensory neurons (By similarity). {ECO:0000250|UniProtKB:Q80XE1}.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding RIC8B 0.496
Publications: 1 Organism: Homo Sapiens