| + |
UCKL1 | down-regulates quantity
chemical modification
|
ATP(4-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280589 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCKL1 | up-regulates quantity
chemical modification
|
ADP(3-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280590 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCKL1 | down-regulates quantity
chemical modification
|
cytidine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280591 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCKL1 | up-regulates quantity
chemical modification
|
cytidine 5'-monophosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280592 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCKL1 | down-regulates quantity
chemical modification
|
uridine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280594 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
UCKL1 | up-regulates quantity
chemical modification
|
uridine 5'-monophosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280595 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35583288 |
Uridine-cytidine kinase like-1 (UCKL-1) is a largely uncharacterized protein with high sequence similarity to other uridine-cytidine kinases (UCKs). UCKs play an important role in the pyrimidine salvage pathway, catalyzing the phosphorylation of uridine and cytidine to UMP and CMP, respectively. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
RNF19B | down-regulates quantity by destabilization
ubiquitination
|
UCKL1 |
0.58 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271590 |
|
|
Homo sapiens |
Natural Killer Cell |
| pmid |
sentence |
| 16709802 |
We demonstrated that both UbcH7 and UbcH8 bind to full-length NKLAM. We demonstrated decreased protein expression and enhanced ubiquitination of URKL-1 in the presence of NKLAM. These data indicate that NKLAM is a RING finger protein that binds Ubcs and has as one of its substrates, URKL-1, thus defining this cytolytic protein as an E3 ubiquitin ligase. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |