3.0
Summary
| Name |  SAE1
|
| Full Name | SUMO-activating enzyme subunit 1 |
| Synonyms | Ubiquitin-like 1-activating enzyme E1A | AOS1, SUA1, UBLE1A |
| Primary ID | Q9UBE0 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SAE1 | form complex 
binding
|
SAE1/SAE2 complex | 0.815 |
| Publications: | 1 | Organism: | In Vitro | |