Summary

Name PI4KB
Full Name Phosphatidylinositol 4-kinase beta
Synonyms PI4K-beta, PI4Kbeta, PtdIns 4-kinase beta, NPIK, PI4K92 | PIK4CB
Primary ID Q9UBF8
Links - -
Type protein
Relations 6
Pathways COVID-19 Causal Network, SARS-CoV ATTACHMENT AND ENTRY
Function Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation PI4KB 0.27
Publications: 1 Organism: Mus Musculus
Tissue: Brain
+ up-regulates img/direct-activation.png phosphorylation PI4KB 0.416
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation PI4KB 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity img/direct-activation.png chemical modification phosphatidylinositol 4-phosphate 0.8
Publications: 1 Organism: Chlorocebus Aethiops
Pathways:COVID-19 Causal Network, SARS-CoV ATTACHMENT AND ENTRY
+ up-regulates img/indirect-activation.png Receptor_mediated_ endocytosis 0.7
Publications: 1 Organism: Chlorocebus Aethiops
Pathways:COVID-19 Causal Network, SARS-CoV ATTACHMENT AND ENTRY
+ up-regulates activity img/indirect-activation.png PI4KB 0.67
Publications: 1 Organism: Rattus Norvegicus