Summary

Name POLG2
Full Name DNA polymerase subunit gamma-2, mitochondrial
Synonyms DNA polymerase gamma accessory 55 kDa subunit, p55, Mitochondrial DNA polymerase accessory subunit, MtPolB, PolG-beta | MTPOLB
Primary ID Q9UHN1
Links - -
Type protein
Relations 2
Inhibitors clofarabine
Function Mitochondrial polymerase processivity subunit. It regulates the polymerase and exonuclease activities promoting processive DNA synthesis. Binds to ss-DNA.

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Relations

Regulator Mechanism target score ℹ
+ clofarabinedown-regulates activity img/direct_inhibition.png chemical inhibition POLG2 0.8
Publications: 1 Organism: Homo Sapiens
+ POLG2form complex img/form-complex.png binding DNA polymerase gamma 0.743
Publications: 1 Organism: In Vitro