Summary

Name GDF2
Full Name Growth/differentiation factor 2
Synonyms GDF-2, Bone morphogenetic protein 9, BMP-9 | BMP9
Primary ID Q9UK05
Links - -
Type protein
Relations 2
Function Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding ACVRL1 0.903
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/indirect-activation.png ALPL 0.26
Publications: 1 Organism: Homo Sapiens