3.0
Summary
| Name |  MED16
|
| Full Name | Mediator of RNA polymerase II transcription subunit 16 |
| Synonyms | Mediator complex subunit 16, Thyroid hormone receptor-associated protein 5, Thyroid hormone receptor-associated protein complex 95 kDa component, Trap95, Vitamin D3 receptor-interacting protein complex 92 kDa component, DRIP92 | DRIP92, THRAP5 |
| Primary ID | Q9Y2X0 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MED16 | form complex 
binding
|
Core mediator complex | 0.781 |
| Publications: | 1 | Organism: | Homo Sapiens | |