Summary

Name CBY1
Full Name Protein chibby homolog 1
Synonyms ARPP-binding protein, Cytosolic leucine-rich protein, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 | ARB1, C22orf2, CBY, PGEA1
Primary ID Q9Y3M2
Links - -
Type protein
Relations 1
Function Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png binding CTNNB1 0.678
Publications: 1 Organism: Homo Sapiens