Summary

Name WNT6
Full Name Protein Wnt-6
Synonyms WNT6_HUMAN
Primary ID Q9Y6F9
Links - -
Type protein
Relations 6
Function Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway.

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Relations

Regulator Mechanism target score ℹ
+ WNT6up-regulates img/direct-activation.png binding LRP5 0.576
Publications: 1 Organism: Homo Sapiens
+ WNT6up-regulates img/indirect-activation.png MYOD1 0.33
Publications: 2 Organism: Homo Sapiens
Tissue: Muscle, Skeletal Muscle
+ WNT6up-regulates img/direct-activation.png binding FZD3 0.613
Publications: 1 Organism: Homo Sapiens
+ WNT6up-regulates img/indirect-activation.png CTNNB1 0.475
Publications: 1 Organism: Homo Sapiens
+ WNT6up-regulates img/indirect-activation.png MYF5 0.315
Publications: 1 Organism: Homo Sapiens