| + |
SUGT1 | up-regulates activity 
binding
|
MIS12 complex |
0.297 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265223 |
|
|
Homo sapiens |
HeLa Cell |
| pmid |
sentence |
| 22869522 |
Here we identify Sgt1, a cochaperone for Hsp90, as a novel Plk1 substrate during mitosis|This phosphorylation event enhances the association of the Hsp90-Sgt1 chaperone with the MIS12 complex to stabilize this complex at the kinetochores and thus coordinates the recruitment of the NDC80 complex to form efficient microtubule-binding sites. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
MIS12 | form complex 
binding
|
MIS12 complex |
0.866 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265190 |
|
|
in vitro |
|
| pmid |
sentence |
| 27881301 |
Human MIS12C (also known as MIND complex or Mtw1 complex in Saccharomyces cerevisiae) contains the MIS12, PMF1, NSL1, and DSN1 subunits |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
NSL1 | form complex
binding
|
MIS12 complex |
0.916 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265191 |
|
|
in vitro |
|
| pmid |
sentence |
| 27881301 |
Human MIS12C (also known as MIND complex or Mtw1 complex in Saccharomyces cerevisiae) contains the MIS12, PMF1, NSL1, and DSN1 subunits |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
DSN1 | form complex
binding
|
MIS12 complex |
0.905 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265189 |
|
|
in vitro |
|
| pmid |
sentence |
| 27881301 |
Human MIS12C (also known as MIND complex or Mtw1 complex in Saccharomyces cerevisiae) contains the MIS12, PMF1, NSL1, and DSN1 subunits |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
PMF1 | form complex
binding
|
MIS12 complex |
0.841 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265192 |
|
|
in vitro |
|
| pmid |
sentence |
| 27881301 |
Human MIS12C (also known as MIND complex or Mtw1 complex in Saccharomyces cerevisiae) contains the MIS12, PMF1, NSL1, and DSN1 subunits |
|
| Publications: |
1 |
Organism: |
In Vitro |
| + |
MIS12 complex | form complex
binding
|
KMN network |
0.882 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-265216 |
|
|
|
|
| pmid |
sentence |
| 18007590 |
The 10-subunit KMN assembly (comprising KNL1, MIS12, and NDC80 complexes, designated KNL1C, MIS12C, and NDC80C) binds microtubules and regulates mitotic checkpoint function through NDC80C and KNL1C, |
|
| Publications: |
1 |
4.0
MIS12 complex
CPX-5643