| + |
TFIIE | up-regulates activity 
relocalization
|
TFIIH |
0.729 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269363 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31064989 |
The heterodimer TFIIE (composed of the TFIIEα and TFIIEβ subunits) seems to play a pivotal role in transcription by directly influencing the transition from initiation to elongation3,4. TFIIE interacts with different factors within the PIC, including Pol II5,6 as well as with DNA immediately upstream of the transcription bubble region7,8. Furthermore, TFIIE seems to influence TFIIH activity9, although it is not clear how this molecular process can occur. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269362 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31064989 |
The heterodimer TFIIE (composed of the TFIIEα and TFIIEβ subunits) seems to play a pivotal role in transcription by directly influencing the transition from initiation to elongation3,4. TFIIE interacts with different factors within the PIC, including Pol II5,6 as well as with DNA immediately upstream of the transcription bubble region7,8. Furthermore, TFIIE seems to influence TFIIH activity9, although it is not clear how this molecular process can occur. |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| Pathways: | Transcription initiation |
| + |
GTF2E2 | form complex 
binding
|
TFIIE |
0.94 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269361 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31064989 |
The heterodimer TFIIE (composed of the TFIIEα and TFIIEβ subunits) seems to play a pivotal role in transcription by directly influencing the transition from initiation to elongation3,4. TFIIE interacts with different factors within the PIC, including Pol II5,6 as well as with DNA immediately upstream of the transcription bubble region7,8. Furthermore, TFIIE seems to influence TFIIH activity9, although it is not clear how this molecular process can occur. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
GTF2E1 | form complex
binding
|
TFIIE |
0.94 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269360 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 31064989 |
The heterodimer TFIIE (composed of the TFIIEα and TFIIEβ subunits) seems to play a pivotal role in transcription by directly influencing the transition from initiation to elongation3,4. TFIIE interacts with different factors within the PIC, including Pol II5,6 as well as with DNA immediately upstream of the transcription bubble region7,8. Furthermore, TFIIE seems to influence TFIIH activity9, although it is not clear how this molecular process can occur. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
TFIIE
CPX-2394