| + |
SCF(TBL1) | down-regulates quantity by destabilization 
polyubiquitination
|
CTNNB1 |
0.72 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271946 |
Lys666 |
LFRMSEDkPQDYKKR |
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271947 |
Lys671 |
EDKPQDYkKRLSVEL |
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
SIAH1 | form complex 
binding
|
SCF(TBL1) |
0.482 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271952 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
TBL1X | form complex
binding
|
SCF(TBL1) |
0.449 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271948 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
APC | form complex
binding
|
SCF(TBL1) |
0.477 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271949 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
SKP1 | form complex
binding
|
SCF(TBL1) |
0.504 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271950 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PUF60 | form complex
binding
|
SCF(TBL1) |
0.324 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271951 |
|
|
Homo sapiens |
HEK-293 Cell |
| pmid |
sentence |
| 20181957 |
Upon UV-induced DNA damage, beta-catenin is recruited for polyubiquitination and subsequent proteasomal degradation by a unique, p53-induced SCF-like complex (SCF(TBL1)), comprised of Siah-1, Siah-1-interacting protein (SIP), Skp1, transducin beta-like 1 (TBL1), and adenomatous polyposis coli (APC). |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
SCF(TBL1)