Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-270592 |
|
|
Homo sapiens |
|
pmid |
sentence |
9922160 |
Myeloperoxidase plays a fundamental role in oxidant production by neutrophils. The enzyme uses hydrogen peroxide to oxidize chloride (Cl-), bromide (Br-), iodide (I-), and the pseudohalide thiocyanate (SCN-) to their respective hypohalous acids.| Our results show that thiocyanate is an important substrate of myeloperoxidase in most environments and that hypothiocyanate is likely to contribute to leukocyte antimicrobial activity. |
|