| + |
COX5B | down-regulates 
|
Cell_cycle_exit |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-253105 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 18701479 |
Together, these data suggest that R-cadherin expression inhibits myogenesis and induces myoblast transformation through Rac1 activation. Therefore, the properties of R-cadherin make it an attractive target for therapeutic intervention in RMS.|R-cadherin expression inhibits myoblast cell cycle exit |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
CDKN1A | up-regulates 
|
Cell_cycle_exit |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-241956 |
|
|
Mus musculus |
Myoblast |
| pmid |
sentence |
| 9388774 |
The upregulation of the cyclin-dependent kinase inhibitor p21 and the dephosphorylation of retinoblastoma protein (pRb) appear to be critical regulatory events for the establishment ,,, the postmitotic ... states [in myoblasts differentiating into mature myotubes] |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
CCND3 | up-regulates
|
Cell_cycle_exit |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-241960 |
|
|
Mus musculus |
C2C12 Cell |
| pmid |
sentence |
| 21898542 |
Our findings suggest that cyclin D3 primes myoblasts for differentiation by enhancing muscle specific gene expression and cell cycle exit |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
Cell_cycle_exit | up-regulates
|
Skeletal_muscle_differentiation |
0.7 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-243206 |
|
|
Mus musculus |
|
| pmid |
sentence |
| 9388774 |
Myogenic precursor cells withdraw irreversibly from the cell cycle as they differentiate into mature myotubes. Cell cycle exit occurs early during the differentiation program and is required for normal expression of the contractile phenotype. |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
3.0
Cell_cycle_exit