SIGNOR has curated the causal relationships that, according to available evidence, are likely to be relevant for the COVID-19 pathology. The perturbations caused by viral infection are integrated into the global cell network. Most of the annotated relationships refers to indirect relationships as few mechanistic details are clarified to date. As new evidences will be published, they will be added to the networks.
SIGNOR 2.0 is part of the COVID-19 Disease Map project